Ketogenic diets may accelerate aging of the heart and kidneys

Scott Keatley, a registered dietitian not involved in the research, provided insights on a study about the effects of ketogenic diets on cellular aging in mice. He emphasized the significance of the findings, highlighting that they offer a mechanistic understanding of how long-term ketogenic diets might lead to cellular aging and dysfunction in critical organs like the kidneys and heart. Keatley pointed out the necessity for careful consideration regarding the duration and composition of ketogenic diets, especially for individuals with existing organ concerns or those at risk for chronic diseases.

He also mentioned the importance of conducting longitudinal trials in humans to confirm whether the findings observed in mice apply to humans. Keatley noted that while ketogenic diets are known for their benefits in managing epilepsy and aiding weight loss, their long-term effects are not fully understood and could pose significant health risks. He stressed that anyone considering such a diet should do so under medical guidance to ensure safety and efficacy.